Workshops
Workshop (W1) – Epidemiologic Intelligence and Forecasting Approaches
Date: Tuesday, December 3, 2024 l Time: 9:00am – 12:00pm
The recent COVID-19 pandemic highlighted the importance of activities related to forecasting, and monitoring of epidemic dynamics and the subsequent risks during an emerging infectious disease event. Recently, global models for the surveillance of emerging threats have been developed combining traditional and non-traditional approaches. Epidemic Intelligence includes activities related to early identification, verification, analysis, assessment, and investigation of health threats.
This workshop will cover state-of-the-art evidence on analytics in epidemic intelligence and forecasting and will focus on real-world experience from around the globe on current practices. The methodology will include group activities engaging all the participants in practical exercises and discussions.
Rokhaya Diagne
Senegal
Auss Abbood
Germany
Jake Hightower
United States
Attendees will discuss current challenges and implementation opportunities for indicator-based (IBS) and event-based (EBS) components.
Global examples of current practices in Epidemic Intelligence in Public Health.
Principles of Modelling applied to infectious diseases forecasting strategies.
Recent advances and perspectives from Artificial Intelligence Techniques, with an emphasis on large language models like ChatGPT.
Network and learn from colleagues experiencing diverse challenges and find opportunities for collaboration. We will be sharing resources that can be used post-workshop to enhance your knowledge and work activities.
A focus on technical limitations and solutions to accelerate the development and implementation of new, practical analytic tools.
Integration of novel strategies to overcome some of the challenges in producing accurate and timely forecasts.
Forecasting Hubs
Influenza and COVID
Performance through ensemble
Collection and understanding of indicators
Synthetic data
LLMs and similar
Relevant use cases
Potential use cases
Ollama as local solution
Non-traditional covariates
Earth Observation
Electronic Health Records
Discussions
What level of analytics do I need? (From R to Cloud)
What are your common challenges?
What are potential modes of collaboration?
Workshop (W2) – AMR Stewardship – What the ID Professional Needs to Know!
Date: Tuesday, December 3, 2024 l Time: 9:00am – 12:00pm
Antimicrobial resistance (AMR) is a growing global health threat, making antimicrobial stewardship (AMS) crucial for healthcare professionals. Antimicrobial Stewardship refers to a set of strategies and practices aimed at promoting the responsible use of antimicrobials to combat AMR and improve patient safety. AMS programs typically involve a multidisciplinary approach, including Infectious Disease physicians, pharmacists, microbiologists, nurses, and other healthcare professionals working together to develop and implement effective antimicrobial stewardship practices.
The workshop aims to build the capacity of healthcare professionals towards the core principles of AMS. It includes the approaches how to establish an AMS program in hospitals. The importance of behavior-change interventions in promoting responsible antimicrobial use and the role of diagnostic stewardship in optimizing antimicrobial prescribing will be discussed. The panel discussion with experienced healthcare professionals will help to understand the practical strategies for overcoming challenges and successfully implementing AMS programs. Real-world examples from healthcare professionals can provide valuable insights into the complexities of AMS implementation and help illustrate effective solutions.
By understanding the importance of AMS, core principles, and implementation strategies, Infectious Disease physicians can lead the way in combating AMR and ensuring patient safety.
Afreenish Amir
Pakistan
Esmita Charani
South Africa
Sasheela Ponnampalavanar
Malaysia
Understand the core principles of antimicrobial stewardship
Learn how to develop and implement an effective AMS program in a hospital setting
Appreciate the role of behavior-change interventions and diagnostic stewardship in AMS
Gain insight into practical challenges and implementation strategies through real-world examples from healthcare professionals
Forecasting Hubs
AMR Stewardship: Principles and Impact on Patient Safety
Establishing AMS program at hospitals, Interventions, and Monitoring
Panel Discussion on Experiences of AMS program in South Africa and outcomes
Role of Behavior-change interventions and Diagnostic stewardship in AMS
Workshop (W3) – Clinical Microbiology – the Future is Here
Date: Tuesday, December 3, 2024 l Time: 2:00pm – 5:00pm
Target audience: Clinical microbiologist, Infectious diseases specialists, Public Health practitioners, Laboratory technologists, General practitioners.
Overview: The workshop will focus on advanced molecular TB diagnostics and use of clinical metagenomics to the clinical microbiology laboratory.
Adrian Brink
South Africa
Margaret Ip
Hong Kong, China
Yahaya Mohammed
Nigeria
Towards precision TB diagnostics – leveraging new laboratory tests to improve patient outcomes
Background:
The WHO’s End Tuberculosis (TB) Strategy targets for 2035 are ambitious, especially considering the significant barrier posed by drug-resistant TB. Through the adoption of current technologies and aggressive scale-up of rapid TB molecular diagnostic tools, there is potential to dramatically reduce the gap of missing cases, particularly those involving drug-resistant tuberculosis. This workshop aims to discuss the opportunities and challenges associated with implementing state-of-the-art TB diagnostics for pragmatic use, incorporating their role in precision medicine. It will cover current TB laboratory trends, and explore ways to fully utilize its potential.
Chairpersons: Dr Stefan Opperman (South Africa) and Prof Margeret Ip (Hong Kong)
Session:
- Detecting Mycobacterium tuberculosis complex with a rapid test for tuberculosis (TB) and rifampin resistance (RIF-R) suitable for point-of-care testing with improved performance in a high-throughput laboratory
Christoffel Opperman (Division of Microbiology, Department of Pathology, University of Cape Town, Groote Schuur Hospital)
The workshop presentation will focus on understanding and interpreting the outputs provided by the platform to utilize the result data to its fullest potential in patient management.
- Comprehensive genetic drug susceptibility testing for rifampicin resistant TB (Using an innovative and integrated culture-free diagnostic kit)
Robin Warren (SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa)
The workshop presentation will focus on a CE-IVD marked assay, capable of testing resistance to 15 anti-TB drugs directly from clinical specimens with a turnaround time of 48 hours, which was recently endorsed by the WHO
- Implementing precision medicine, prevention, and public health to reduce the burden of drug-resistant tuberculosis. (PARR-TB concept).
Annelies Van Rie (Global Health Institute, Family Medicine and Population Health, University of Antwerp, Belgium)
The workshop presentation will focus on the PARR-TB concept which aims to evaluate the implementation of whole genome sequencing and a digital platform that generates automated, reliable, and actionable outputs into the existing healthcare infrastructure, to facilitate to use of precision medicine, prevention, and public health to combat the RR-TB epidemic.
Learning outcomes:
- Understand principles and methodologies of advanced Point of Care technologies and the culture-free diagnostic assay compared to its predecessors
- Strengths, weaknesses, and differences between targeted next generation sequencing and whole genome sequencing (WGS) for routine diagnosis and management of rifampicin resistant TB.
- Determine hetero-resistance and relationship between genotype and phenotype in TB drug resistance through advanced sequencing techniques
- Develop troubleshooting skills to address errors, discordant and invalid molecular results.
- Utilizing WGS data to guide intensified contact tracing and targeted source investigation
- Understanding the essential components required for the use of WGS for precision medicine and precision prevention
Clinical metagenomics (CMg) – Exploiting molecular laboratory advancements and bioinformatics
Background:
This workshop will introduce attendees to clinical metagenomics (CMg) through the lens of a limited resource setting. Its applications in surveillance and routine diagnostics will be explored and available technology introduced. Wet-lab workflows will be discussed with emphasis on selection of an appropriate workflow for the desired outcomes. The workshop will also address the processing and interpretation of sequencing data with delineation of required resources and currently available tools. Finally, integration of CMg into a diagnostic medical microbiology laboratory will be discussed, with reference to tools, institutional practices and barriers to implementation that operators will need to navigate.
Chairperson: Dr Hafsah Tootla (South Africa) and Prof Yahaya Mohammed (Nigeria)
Session:
- Samuel Yingst, Global Alliance for Preventing Pandemics, Columbia University
- CMg Wet Lab: Enrichment and Illumina
Alltalents Murahwa, Medical Virology University of Cape Town - CMg Wet Lab: Depletion and Nanopore
Philippe Selhorst, Institute of Tropical Medicine Antwerp, Institute of Tropical Medicine Antwerp - CMg In the clinic: Interpretation of CMg result
Gert Marais, Medical Microbiology University of Cape Town and Crick Africa Network Fellow
Learning Outcomes:
- Applications of CMg in low resource settings
- Available wet-lab CMg workflows and required resources
- Principles of sequencing data analyses, quality control,data storage, and database selection
- Manipulation of sequencing data for research purposes and diagnostic purposes
- Integration of sequencing data, clinical data and routine laboratory data
- Data protection, privacy and sharing
- Emerging trends in clinical metagenomics
- Potential impact of artificial intelligence and machine learning in the advancement of clinical metagenomics
- Challenges associated with clinical metagenomics (data analysis
Workshop (W4) – The Pharmacist’s Role in the Infectious Diseases Team
Date: Tuesday, December 3, 2024 l Time: 2:00pm – 5:00pm
Antimicrobial stewardship (AMS) initiatives offer enriching opportunities for pharmacists to engage with various audiences preserving antimicrobials for infection care. Given this, the 20th International Congress on Infectious Diseases (ICID) features a pre-conference workshop on engaging stakeholders in AMS.
Oluchi Mbamalu
South Africa
Angeliki Messina
South Africa
Debra Goff
United States
The objectives of the workshop are to:
Engage with stakeholders on stewardship advances in healthcare settings
Facilitate knowledge sharing and ideas between and among antimicrobial stewards
Highlight opportunities for AMS in different settings and with different stakeholders
Features: We welcome you to our interactive workshop on AMS featuring:
AMS advocacy
Digital tools for AMS support
Challenges in AMS implementation
Employing available resources for AMS
AMS mentors and processes in various settings
Patient, family and community AMS engagement
We plan to have three presentations – with each presentation covering one or more of the topics featured. Each present would last for about 35 minutes, with an additional 20 – 25 minutes for Q&A or a small interactive activity. For the 3-hour activity we will structure the workshop such that there will be great engagement and discussions/opportunities for participants to speak/share!